Osteopromotive Coatings: Diatom-Inspired Silica Nanostructure Coatings with Controllable Microroughness Using an Engineered Mussel Protein Glue to Accelerate Bone Growth on Titanium-Based Implants

Silica nanoparticles can create nanostructures with surface topography and osteoinductivity. Researchers, including Chang Sup Kim and Hyung Joon Cha, developed a diatom-inspired silica-nanoparticle coating for titanium surfaces. This coating uses a mussel protein glue to control micro-roughness, enhancing osteogenic cell behavior and promoting bone tissue formation and maturation.

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